Size-Controlled Nanomicelles of Poly(lactic acid)–Poly(ethylene glycol) Copolymers with a Multiblock Configuration
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چکیده
منابع مشابه
Size-Controlled Nanomicelles of Poly(lactic acid)–Poly(ethylene glycol) Copolymers with a Multiblock Configuration
The ability to control the micelle size of poly(lactic acid) and poly(ethylene glycol) (PLA–PEG) block copolymers is important for controlling their circulation in blood cell recognition, drug release and therapeutic effects. We successfully controlled the micelle size by changing the block number of copolymers (multiblock index). PLA–PEG multiblock copolymers with multiblock indexes ranging fr...
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Molecular-dynamics simulations are used to study the phase behavior of a single linear multiblock copolymer with blocks of Aand B-type monomers under poor solvent conditions, varying the block length N , number of blocks n, and the solvent quality (by variation of the temperature T ). The fraction f of A-type monomers is kept constant and equal to 0.5, and always the lengths of A and B blocks a...
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ژورنال
عنوان ژورنال: Polymers
سال: 2015
ISSN: 2073-4360
DOI: 10.3390/polym7061177